Mtdna haplogroup h1a1 It has been often stated that the overall pattern of human maternal lineages in Europe is largely uniform. 16519 from H1, 73 & 16162 from H1a, and 16209 from H1a1. Haplogroup is the term scientists use to describe a group of mitochondrial (maternal haplogroups) or Y-chromosome (paternal haplogroup) sequences that are more closely related to one another than to others. mtdna haplogroup: h1a1 Joan Hurst was born in 1567/8 in Henlow, Bedford, England, the daughter of William and Rose Hurst. There were three mtDNA haplogroup K1a, two T2b, one H3, and one U5. A study conducted by Maruszak et al. 4 Distribution of mtDNA haplogroups H1 & H3 in Europe, North Africa and the Middle East H5 1/7 Haplogroup H5 is also found throughout western Eurasia and North Africa, but has a more Central European focus. R0 sub-lineages are badly defined in the control region and therefore, the analysis of diagnostic coding region polymorphisms is needed in order to gain resolution in population and medical studies. (2011 bis) tested 7 skeletons from a 7,000-year-old Neolithic site from the Avellaner Cave in Cogolls, Catalonia, Spain. M and N are the signature maternal haplogroups that define the theory of the recent African origin of modern humans and subsequent early The distribution of mitochondrial DNA haplogroup H in Aug 12, 2019 · An expectation maximization approach was used to determine mtDNA haplogroup mixture proportions for samples collected at each different geographic location. Several hypotheses have been proposed on the origin and the expansion times of some R0 sub-lineages, which were partially inconsistent with each other. The testing of matrilineal relatives of Lincoln's mother, Nancy Hanks, provided evidence that the the 16th president of the United States belonged to the very rare haplogroup X1c. Our results show reasonable agreement mtdna haplogroup: h1a1 Elizabeth Tilley came on the Mayflower , at the age of about thirteen, with her parents John and Joan (Hurst) Tilley. mtDNA H Subhaplogroups Found in WikiTree. Although your maternal haplogroup reflects just one of your many ancestral lineages, it carries information about that lineage over tens of thousands of years. I know we are part of H and H1a but I haven't seen very many with H1a1 so far. I've researched H1av1 and H4 apparently found in neothilic Spain specifically Basque region where my maternal lineage comes from (mum is o negative and irish ancestry, must have been from Basque movement into Ireland. Am. org. 2. Jun 6, 2019 · Haplogroup Defining Mutations. Unlike other branches of the mega-haplogroup H, the defining mutation for H1 (3010A) has likely happened many times in the history of H. Haplogroup H1a is descended from haplogroup H. Nearly 10% of Europeans can trace their maternal ancestor to Haplogroup T. However, previous studies have left unanswered questions about the exact parental population groups in South Asia. Is that certain? mtDNA haplogroup # Alden, John: Priscilla Mullins: H6a1a9 +T204C +G6182A 5 H1a1: 4 presumably never married: Desire Minter More children Ellen, Jasper, Mary The large majority of Ashkenazi mtdna branches has clear SNPs that can be used to recognize the people with Ashkenazi heritage. Perhaps you have been poring over your DNA test results from 23andMe and you have come across an unfamiliar set of words: haplogroup H. The differences among the Jewish populations in mtDNA haplogroup frequencies indicates that the Jewish groups formed independently around (at least) eight small, distinct nuclei of women. [2] An enormous haplogroup spanning all the continents, the macro-haplogroup M, like its sibling the macro-haplogroup N, is a descendant of the haplogroup L3. [3] Sep 18, 2020 · If your haplogroup isn’t showing, you could be downstream of the Viking haplogroup, so you’ll need to use the Y DNA Block Tree (for Big Y testers) or public haplotree, here. We are working together to understand the dynamics of a lineage that has its oldest branches in Central Asia, the Indian subcontinent, and across Northern Africa yet has a large population from the Iberian peninsula up to Scandinavia. MtDNA Haplogroup H1a1 (0, 56, 0) MtDNA Haplogroup H1j9 [hide person profiles] Person Profiles (86) A. HG: haplogroup; mtDNA: mitochondrial DNA; CR: control region. So, we need to stick together. If you have tested your mtDNA and your mtDNA test reveals that you are H1a1, please add this category to your own profile If a family member has tested their mtDNA and their test reveals they are H1a1, please add this category to their profile Add this category to the direct FEMALE ancestors of the person who took the test---- Aug 15, 2007 · Haplogroup H1a1 mdillow31 H1a1 I joined the Haplogroup H Project and am on Mitosearch. The term haplogroup is a combination of haplotype and group. They then name subclades (branches) with alternating numbers and letters: H, H1, H1a, H1a1, etc. For the hierarchy of these subhaplogroups see H under mtDNA subtree R0 at PhyloTree. H1 encompasses an important fraction of Western European mtDNA lineages, reaching its local peak among contemporary Basques (27. mtDNA H subhaplogroups of DNA testers found in their WikiTree profiles which include results in MitoSearch. Mutations in Different Haplogroups are Not Equal How are mtDNA haplogroups named? In general, scientists name mtDNA haplogroups according to their major branch with a capital letter. Jul 6, 2013 #9 @zanipolo Your suggestion of H2a2a* as follows: H2a2a is a subgroup of H2 IntroductionHaplogroup H is the most common in Jan 24, 2007 · Comparison of overall haplogroup distribution (R × C test of independence) revealed significant differences among the three Jewish populations (RU, Poland and Romania, P=0. Nov 24, 2024 · mtDNA Results H1a1. , so it is a VERY old haplogroup. Hum. Genet. In addition, according to the H1 mtGenome Project the H1a1 clade originated approximately 2500 B. Thanks Maria for emailing me. Yet this uniformity may also result from an insufficient depth and width of the phylogenetic analysis, in particular of the predominant western Eurasian haplogroup (Hg) H that comprises nearly a half of the European mitochondrial DNA (mtDNA) pool. Is there a mtDNA haplogroup project associated with either H1a1, H1a, or H1? In human mitochondrial genetics, Haplogroup H5 is a human mitochondrial DNA (mtDNA) haplogroup descended from Haplogroup H (mtDNA). The Nancy Hanks Lincoln mtDNA Study traced back the mitochondrial DNA lineage of Abraham Lincoln (1809-1865). , 2013) yet still found among modern Ashkenazi Jews. Oct 9, 2016 · I am interested in the mtDNA of Elizabeth (Tilley) Howland, who came over on the Mayflower and later married John Howland. 23, 1672/3 and instead played the useful role of grandma while living with her daughter Lydia Brown in Swansea. Its numerical success nears half the population Jan 1, 2014 · The T16189C polymorphism, defining haplogroup H1a6, H1b, H1f, H1g, H1j9, H1k, H1y, H1z, H1aa, H1ab, H1ac, H1ad, H1ap1, H1cc, H1c3b, H2a2a1g, H3av and H96, lowers the Apr 2, 2009 · Background R0 embraces the most common mitochondrial DNA (mtDNA) lineage in West Eurasia, namely, haplogroup H (∼40%). Nevertheless, members of haplogroup I1c carry Altogether, the project has more than 11,000 participants, making it the largest public mtDNA Haplogroup project. The haplogroups reported at a high level (e. E. Apr 2, 2009 · Some haplogroups show slight differences in frequency. It is therefore likely that it underwent its earliest diversification in mainland East or South East Asia. If you belong to subclade T2, please join the T2 project instead. Mitochondrial 'Eve' Emerged 151,600 to 233,600 years ago Hg-H1 TMRCA 10,000 BP. LOL ! The Tuareg of the Fezzan region (Libya) are characterized by an extremely high frequency (61%) of haplogroup H1, a mitochondrial DNA (mtDNA) haplogroup that is common in all Western European populations. You’re in the right place to learn more about what this Dec 20, 2023 · Interestingly, several haplogroups found among Ashkenazi Jews, such as mitochondrial haplogroup K1a1b1a and Y-chromosomal haplogroup R1a1a1b1a, are relatively rare in other populations. Haplogroup H is the dominant European mtDNA haplogroup. Thus the mtDNA "signature" is not limited to descendants of Elizabeth (Tilley) Howland, but predate her by several millennia. Methodology/Principal Findings We sequenced the first hypervariable segment Origin and Expansion of Haplogroup H, the Dominant Human Loading Then, by matching these mtDNA variant sites, it was also discovered that all seven heteroplasmic variants at around the 60% heteroplasmy level in II-4 to be maternally inherited from I-10 (with a haplogroup of H1a1, SI Appendix, Fig. Its ancestral haplogroup was Eurasian haplogroup R. Her parents, and her aunt and uncle Edward and Agnes Tilley, all died the first winter, leaving her orphaned in the New World. Feb 15, 2024 · “Elizabeth Tilley Howland: a widow for 15 years” By Robert F. Nov 28, 2012 · The presence of Indian-specific Y-chromosome haplogroup H1a1a-M82 and mtDNA haplogroups M5a1, M18 and M35b among Roma has corroborated that their South Asian origins and later admixture with Near Eastern and European populations. Most of the people identified in the table below as belonging to such a high-level haplogroup would, upon, full mtDNA testing, be determined to belong to an mtDNA cluster within such haplogroup. Jayne provides us with an overview of mtDNA haplogroup H and what it can tell you about your ancestry. 017). HG assignments with full-length and CR sequences of mtDNA using Haplotracker and HaploGrep 2. Using an unplanned Jul 5, 2019 · I've found out I've inherited Haplogroup H, specifically H1, H1a, H1aV1, and H4. The number of Ashkenazi mtdna branches is larger than Ashkenazi Y-DNA branches. [14] Haplogroup M is relatively young, having a younger most Haplogroup I is a human mitochondrial DNA (mtDNA) haplogroup. These data are based on the cumulative number of estimated HGs consistent with the original Phylotree HG assignments at a rank as tested with 8,216 full-length and CR mtDNA sequences. Sep 15, 2016 · Yes, most likely your mtDNA haplogroup is H1a1 or one of its subclades, since you have. I am sure we will receive a good report on our H1a1. 75, 910–918 (2004) . 3. Huber For 15 years—or almost 20 percent of her life—Elizabeth Tilley Howland was a widow. mtDNA Haplogroup Mutations. . Distribution of mtDNA haplogroups H1 & H3 in Europe, North Africa and the Middle East H5 1/7 Haplogroup H5 is also found throughout western Eurasia and North Africa, but has a more Central European focus. She never remarried after her husband and fellow Mayflower passenger died on Feb. Harvey Amiott 16 Aug 1932 - 25 Mar 2013 The two I2a men belonged to mtDNA haplogroup H1 and H3. The greatest variety of haplogroup B is in China. I note where a couple of mtDNA descendants have shown where Elizabeth had mtDNA H1a1. She married first to Thomas Rogers in 1593 (not related to the Mayflower passenger Thomas Rogers). mtDNA Results H1a1. WikiTreers are encouraged to add to this list. The primary branch H1 (H-M69) and its subclades is one of the most predominant haplogroups amongst populations in South Asia , particularly its descendant H1a1 (M52). All mtDNA haplogroups found outside of Africa are descendants of either haplogroup N or its sibling haplogroup M. MITOMAP's Haplogroup T; FamilyTreeDNA's mtDNA Haplotree: Haplogroup T; Spread of Haplogroup T, from National Geographic; Genetic Genealogy: A Personal Perspective on Tara, Karelians and Kent, England; Analysis of a Haplogroup T sequence (T5/T2) Phylogenetic Networks for the Human mtDNA Haplogroup T Archived 2008-05-31 at the Wayback Machine Jul 4, 2008 · Background Nearly half of the West Eurasian assemblage of human mitochondrial DNA (mtDNA) is fractioned into numerous sub-lineages of the predominant haplogroup (hg) R0. Among 23andMe research participants, haplogroup H1a is commonly found among populations in the United Kingdom and Ireland. S2), whereas the other 13 variants at around the 40% heteroplasmy level came from his father (I-1 with a May 26, 2012 · mtDNA haplogroup H1a1. For information on the mutations which characterize each haplogroup, see the table of mtDNA haplogroup motifs. Welcome to the H1 mtDNA Full Genomic Sequence (mtGenome) Project. H5 is defined by T16304C in the HVR1 region and 456 in the HVR2 region. Here we describe the phylogenetic structure and genetic variety of hg R0 Jul 14, 2004 · Abstract. Famous H individuals Various matrilineal descendants of Empress Maria Theresa were tested and confirmed to belong to the same haplogroup (H with the mutations 152C, 194T and 263G, which most probably corresponds to the H3s subclade). If you are defined as T only, please also join the T mtDNA other (not T1 or T2) project. The PBS TV series Faces of America disclosed that he belonged to mtDNA haplogroup C. If we look at the largest Y-DNA branches, 25 Y-DNA branches give 75% of the Ashkenazi Y-DNA; 35 mtDNA branches give 75% of the Ashkenazi This project is for anyone belonging to mtDNA Haplogroup T1. Lacan et al. The Haplogroup H&HV mtGenome Project: H1 - mtDNA Member Distribution Map. Please show only one example per subhaplogroup. The highest frequencies of H1 are observed in the Iberian peninsula, south-west France and Sardinia. See also [] Human mitochondrial genetics; Cambridge Reference Sequence; Human Y-chromosome DNA haplogroup * Molecular phylogeny Apr 23, 2013 · The molecular dissection of mtDNA haplogroup H confirs that the Franco-Cantabrian glacial refuge was a major source for the European gene pool. Haplogroup B is believed to have arisen in Asia some 50,000 years before present. The mutation defining haplogroup T happened some time around 29,000 years ago, probably in the East Mediterranean region. The severity of these demographic events was sufficiently great to drive an unusual pattern of geographic variation among the Jewish populations. For a graphical depiction of haplogroup branching, see Vincent Macaulay's mtDNA haplogroup skeleton. Using the Build 17 table published by Family Tree DNA that identifies the mutations required to assign an individual to a specific haplogroup or subhaplogroup, you can determine why you were assigned to a specific haplogroup and subgroups. Our direct maternal ancestors have passed on their mitochondrial DNA (mtDNA) generation after generation. These signatures are currently being identified, and GSMD policies on the mtDNA requirements are being proposed. This project hopes to identify the mtDNA genetic signatures based on proven descendants. We know from the results of four mtDNA tests from three different daughters of Elizabeth (Tilley) Howland, the matrilineal (all female) line falls under haplogroup H1a1 with no extra mutations. C. J. These distinct genetic lineages may have been influenced by genetic drift, founder effects, or selection pressures specific to the Ashkenazi Jewish population. For example, while haplogroup H sums ∼39% of the total mtDNAs in Catalonia and Cantabria, it makes-up ∼44% of the mtDNA pool in Galicia. Mitochondrial DNA haplogroups or subclades can sometimes reveal some potential medical conditions (see diseases associated with mtDNA mutations). Oct 13, 2016 · The mtDNA signature is an exact match to Haplogroup H1a1 with no extra markers (with the exception of the flippy 315C & 16519C). The mtDNA test results focus on maternal lineages down to a daughter or son of one of the proven female Mayflower descendants. g. , Brotherton et al. T1 and T2 split from each others some 21,000 years ago, toward the end of the Last Glacial Maximum (c. H; H1 * H1a Like its sibling macrohaplogroup M, macrohaplogroup N is a descendant of the haplogroup L3. (2014) analysed the mtDNA of 395 elite Polish athletes (213 endurance athletes and 182 power athletes) and 413 sedentary controls and found that haplogroup I is among the most underrepresented mtDNA types among endurance athletes at the Olympic/World Class level. H1a1 T6365C, T16209C H1a1a T4639C H1a1a1 G10993A H1a1b T7961C Haplogroup H (Y-DNA), also known as H-L901/M2939, is a Y-chromosome haplogroup. 8%). The clade also occurs at high frequencies elsewhere in the Iberian Peninsula, as well as in the Maghreb (Tamazgha). All lines began with our common maternal ancestor in Africa. In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Six paternal lineages (Y-DNA) were identified including five G2a and one E1b1b1a1b (E-V13). Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree. It is believed to have originated about 21,000 years ago, during the Last Glacial Maximum (LGM) period in West Asia (( Olivieri 2013 ); Terreros 2011 ; Fernandes 2012 ). That table identifies those Ashkenazi mtDNA haplogroups by name (YFull's MTree, FTDNA, and 23andme often use different names for the same haplogroups), frequency (based on Wim Penninx's 2019 analysis of mtDNA frequencies in the Ashkenazi population, with modifications discussed in the note below), and the SNPs that define each haplogroup at its Mar 22, 2023 · mtDNA haplogroup H is one of the haplogroups you may find in your DNA, specifically your mtDNA. The column for haplogroup U includes U1, U6, U7, U8 and U9. 26,500 to 19,000 years before present). All mtDNA haplogroups considered native outside of Africa are descendants of either haplogroup M or its sibling haplogroup N. Complete sequencing of 62 mitochondrial DNAs (mtDNAs) belonging (or very closely related) to haplogroup H revealed that this mtDNA haplogroup—by far the most common in Europe—is subdivided into numerous subhaplogroups, with at least 15 of them (H1–H15) identifiable by characteristic mutations. Human populations along the westernmost Mediterranean coasts, which were settled by individuals from two continents separated by a relatively narrow body of water, show the highest frequencies of mitochondrial Origins & History. ) Discover the countries of origin for each branch of the mtDNA Haplotree using the world's largest mtDNA database containing keyboard_arrow_right H1a1. H1 is found throughout Europe, North Africa, the Levant, Anatolia, the Caucasus, and as far as Central Asia and Siberia. If you’ve taken the Big Y test, click on the Block Tree on your results page and then look across the top of your results page to see if the haplogroup in question is Haplogroup is the term scientists use to describe a group of mitochondrial (maternal haplogroups) or Y-chromosome (paternal haplogroup) sequences that are more closely related to one another than to others. Jul 26, 2016 · ber of haplogroups with ambiguous geographic origins, we conducted a detailed investigation into a haplogroup that is overwhelmingly Euro-pean (e. To define how and when H1 spread from Europe May 19, 2017 · Background The structure of haplogroup H reveals significant differences between the western and eastern edges of the Mediterranean, as well as between the northern and southern regions. Haplogroup V reaches its highest frequency in Cantabria, ∼9%, and decrease substantially in Galicia (∼4%), and in Catalonia (∼3%). , as H or K) are likely based upon HVR1 or HVR1 and HVR2 mtDNA testing rather than full (FMS) mtDNA testing. According to the H1 mtGenome Project, Haplogroup H1a1 dates back about 2500 B.
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